Oxidation-Responsive, EuII/III-Based, Multimodal Contrast Agent for Magnetic Resonance and Photoacoustic Imaging

نویسندگان

  • Lina A. Basal
  • Yan Yan
  • Yimin Shen
  • E. Mark Haacke
  • Mohammad Mehrmohammadi
  • Matthew J. Allen
چکیده

We report, for the first time, a multimodal, oxidation-responsive contrast agent for magnetic resonance imaging and photoacoustic imaging that uses the differences in the properties between Eu in the +2 and +3 oxidation states. The enhancement of contrast in T1-weighted magnetic resonance and photoacoustic imaging was observed in the +2 but not in the +3 oxidation state, and the complex is a known chemical exchange saturation transfer agent for magnetic resonance imaging in the +3 oxidation state.

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عنوان ژورنال:

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2017